Brain organoids replicate key events in human brain development
A single-cell analysis of 3D models of the human cerebral cortex suggests they can be used to study important brain processes that have been difficult to investigate
New technique reveals single cell gene regulatory networks
Researchers can utilize this new framework to study how the epigenome influences gene expression in single cells over time
Improving stem cell-derived pancreatic cells with genetic engineering
HSCRB scientists advance Type 1 diabetes therapy by protecting cells from immune attack and stress
Different autism risk genes, same effects on brain development
HSCRB and Broad researchers use 3D, miniature models of the human brain to advance disease understanding
Genomic sequencing that preserves cells’ locations within tissues
New technique allows researchers to better understand spatial differences in complex tissues such as tumors
A new therapy for treating Type 1 diabetes
A stem-cell-derived replacement therapy shows unprecedented early results in treating Type 1 diabetes
New gene-transport system gets more drugs to sick muscles
Reduces the risk of liver damage and other serious side effects
A detailed atlas of the developing brain
Harvard and Broad researchers combine single-cell genomic technologies to map the mouse cortex
Discovery of sugar-coated RNA molecules opens up new area of cell biology
New connection between metabolism and red blood cell development
Harvard researchers identify mechanism with therapeutic potential for anemia