Out with the Old (Neurons), In with the New
New research from the Macklis lab finds that just a few thousand neurons orchestrate evolutionarily advanced forelimb and digit dexterity.
HDRB 2023 Graduate Thankful for HSCRB Support, Mentorship
Reese Caldwell reflects back on his time in the HSCRB department
A 14-year Incubation
In early 2023, Sam Wattrus, opened his own lab at Massachusetts General Hospital, becoming the first human developmental and regenerative biology concentrator to establish research lab
Meet the HSCRB Faculty: Ryan Flynn
Ryan Flynn, MD, PhD, is an Assistant Professor in HSCRB and a Principal Investigator in the Stem Cell Program at Boston Children’s Hospital. Learn more about Ryan and his research below.
Brain organoids replicate key events in human brain development
A single-cell analysis of 3D models of the human cerebral cortex suggests they can be used to study important brain processes that have been difficult to investigate
New technique reveals single cell gene regulatory networks
Researchers can utilize this new framework to study how the epigenome influences gene expression in single cells over time
Improving stem cell-derived pancreatic cells with genetic engineering
HSCRB scientists advance Type 1 diabetes therapy by protecting cells from immune attack and stress
Different autism risk genes, same effects on brain development
HSCRB and Broad researchers use 3D, miniature models of the human brain to advance disease understanding
Genomic sequencing that preserves cells’ locations within tissues
New technique allows researchers to better understand spatial differences in complex tissues such as tumors
A new therapy for treating Type 1 diabetes
A stem-cell-derived replacement therapy shows unprecedented early results in treating Type 1 diabetes