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Rubin Lab

Rubin Lab People

Photo of Lee Rubin

Lee Rubin investigates the key molecular mediators of different neurodegenerative diseases, with the ultimate goal of finding effective preclinical therapeutic candidates.

Photo of Jane LaLonde

Jane is our Lab Administrator, providing logistical and organizational support to Lee Rubin and members of the laboratory.

Research Scientists

Photo of Richard Krolewski

Rich is a movement disorders neurologist using dopamine neurons made from the iPSCs of Parkinson’s Disease patients to better understand how gene/environment interactions influence disease pathogenesis and inform new treatment options.

Photo of Michelle Sauer

Michelle specializes in assay development and high-throughput screening and runs the screening operations in the lab.

Photo of Feodor Price

Feo’s research is translational in nature and geared towards studying how adult skeletal muscle stem cells are involved in regulating muscle regeneration.

Postdoctoral Fellows

Photo of Junghyun Lee

Junghyun is studying the pathways regulating blood-brain barrier during development and aging. His work is focused on developing in vitro model of brain endothelial cells using human iPSCs.

Graduate Students

Photo of Francesco Limone

Francesco is a visiting PhD student at HSCRB and the Stanley Center at Broad Institute. His work focuses on the understanding of molecular mechanisms underlying neuroinflammation, neurological disorders and aging using human iPSC-derived neuronal cells, mouse models, and computational approaches.

Recent Alumni

Photo of Scott Logan Lipnick

Scott Lipnick is a principal scientist in the Rubin Lab and an Instructor in Biomedical Informatics at Harvard Medical School. He is also a member of the Massachusetts General Hospital Center for Assessment Technology and Continuous Health (CATCH).

Photo of Chen Wu

Chen Wu is looking for a novel and specific drug to improve the survival of motor neurons for ALS therapeutics. By studying the targets of the drug, he hopes to explain the mechanism and how the downstream signal pathways work.

Photo of Gizem Rizki

Gizem is a research scientist who specializes in assay development and high-throughput screening and runs the screening operations in the lab. She collaborates with screeners to set up and execute small molecule screens to identify therapeutic targets of neurodegenerative, neuropsychiatric, and other diseases as well as unravel biological insights into disease mechanisms through screening.

Photo of Kathleen Pfaff

Kathy is the Senior Research Manager in the Rubin Laboratory. She advises individuals and teams on their research projects, serves as the liaison between the lab and external collaborators, and provides operational and financial oversight.

Photo of Brittany Mayweather

Brittany’s research investigates the physiological role of endogenous GDF11 during adult neurogenesis and the therapeutic implications of manipulating GDF11 signaling.

Photo of Michelle Watts

Michelle is a senior graduate student in Harvard’s Biological and Biomedical Sciences program. Her research focuses on developing predictive models of ALS using patient cells to investigate convergent protective mechanisms behind therapeutic compounds.

Photo of Ceren Ozek

Ceren is a postdoctoral fellow studying the beneficial vascular and neural effects of GDF11 on healthy aging and neurodegenerative diseases, specifically Alzheimer’s Disease, using transgenic mice as model organisms.

Photo of Methodios Ximerakis

Methodios is looking to identify cellular and molecular mechanisms that trigger brain aging and rejuvenation by using single-cell transcriptomics.

Photo of Hye Young Shin

Hye Young Shin studies early changes during human motor neuron degeneration, using automated live cell imaging. She also uses long-term, live imaging of motor neurons differentiated from hESCs and iPSCs for survival assay development and its application in drug screening.

Photo of Francesca Rapino

Francesca is a postdoctoral fellow at HSCRB and at the Broad Institute. Her work seeks to understand the role of complement component in schizophrenia, using iPSC derived neuronal cultures and small molecule screening.

Join Our Lab

We are always seeking highly motivated students and postdoctoral fellows who are passionate about understanding the biological basis of neurological disease. Postdoctoral candidates are welcome to send a research statement and CV to Lee Rubin.
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