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Lee Lab

Lee Lab Research

Our approach is to understand human problems and design solutions in the laboratory, and demonstrate the effectiveness of these solutions in vivo.

Areas of Investigation

Heart cells beating

Heart regeneration with stem cells

We explore ways to use induced pluripotent stem (iPS) cells to create cardiomyocytes that could be used in clinical treatments, and potential approaches to stimulating endogenous heart regeneration in adult mammals.
Animation of a protein structure

The aging heart

Because aging is a major factor in the worldwide heart failure epidemic, we study factors that contribute to cardiac aging and heart failure.
Arrestin family

Arrestin proteins and metabolism

We investigate how the alpha arrestins, a family of conserved proteins, regulate mammalian metabolism.

DNA adducts in aging

We collaborate with Professor Peter Dedon of MIT to study new DNA molecules in the aging heart and brain.
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