Lee Lab Research
Our approach is to understand human problems and design solutions in the laboratory, and demonstrate the effectiveness of these solutions in vivo.
Areas of Investigation
Heart regeneration with stem cells
We explore ways to use induced pluripotent stem (iPS) cells to create cardiomyocytes that could be used in clinical treatments, and potential approaches to stimulating endogenous heart regeneration in adult mammals.
The aging heart
Because aging is a major factor in the worldwide heart failure epidemic, we study factors that contribute to cardiac aging and heart failure.
Arrestin proteins and metabolism
We investigate how the alpha arrestins, a family of conserved proteins, regulate mammalian metabolism.
DNA adducts in aging
We collaborate with Professor Peter Dedon of MIT to study new DNA molecules in the aging heart and brain.