Rich Lee seeks to understand heart failure and metabolic diseases that accompany human aging, and translate that understanding into therapies. Lee is an active clinician, regularly treating patients at Brigham and Women’s Hospital.
Timothy Fenn is a faculty assistant, supporting Lee, McKinley, and Strominger Labs. He has a BA in Humanities from New York University, and in his off time enjoys books, music and basketball
Alexander is focused on identifying the causal role of mitochondrial DNA mutations in aging and cardiovascular disease, as well as the development of therapeutic interventions to restore or improve mitochondrial function and disease outcomes.
Megan is investigating the role and molecular mechanisms of alpha arrestin domain-containing protein (ARRDC4 and Txnip) on glucose metabolism in vivo and ex vivo.
Fang is focused on developing immune-compatible mature cardiomyocytes from iPSC and understanding biological underpinnings of cardiovascular disease through analysis of myocardial transcriptomics.
Yijun is a G3 graduate student in the Lee Lab. She studies identified and novel DNA adducts in mammalian cells by defining their structure, formation, and repair mechanisms.
Eve is interested in human genetics and is working on identifying the causative role of mitochondrial DNA mutations in aging and cardiovascular disease using mature cardiomyocytes derived from induced pluripotent stem cells.
Morgan works on different projects in the lab with the focus of developing mature cardiomyocytes derived from human induced pluripotent stem cells for future treatment of cardiac disease.
