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Lee Lab

The Lee Lab in May 2019, outside the Sherman-Fairchild/Bauer complex at Harvard University.
Principal Investigator

Richard Lee, M.D.

Photo of Rich Lee in his lab at Harvard

Rich Lee's laboratory seeks to understand heart failure and metabolic diseases that accompany human aging, and to translate that understanding into therapies, including stem cell transplantation strategies and new biological agents. Lee is an active clinician, regularly treating patients at Brigham and Women’s Hospital.

Image of Richard Lee, M.D.

Richard Lee, M.D.

  • Professor of Stem Cell and Regenerative Biology
  • Professor of Medicine
    Harvard Medical School
  • Senior Physician
    Brigham and Women's Hospital
  • HSCI Program Leader, Cardiovascular Diseases
    Harvard Stem Cell Institute


Richard T. Lee is Professor of Stem Cell and Regenerative Biology at Harvard University and Professor of Medicine at Harvard Medical School. He is a 1979 graduate of Harvard College in Biochemical Sciences and received his M.D. from Cornell University Medical College in 1983. Lee completed his residency in 1986 and cardiology fellowship in 1989, both at Brigham and Women’s Hospital in Boston. He is certified by the American Board of Internal Medicine in cardiovascular disease. Lee is Leader of the Cardiovascular Diseases Program of the Harvard Stem Cell Institute. He is also a member of the Editorial Board of the journal Circulation.

Dr. Lee has published over 270 peer-reviewed articles based on his research, and teaches undergraduates at Harvard College. In addition, he is an active clinician. He regularly treats patients as a cardiologist at Brigham and Women’s Hospital.

Lab Overview

The Lee Laboratory uses biotechnologies to discover and design new approaches to cardiovascular and metabolic diseases. We work at this interface using a broad variety of techniques in genomics, stem cell biology, and molecular biology. Our approach is to understand human problems and design solutions in the laboratory, and then we demonstrate the effectiveness of these solutions in vivo.

Ongoing projects in the laboratory include studies of cardiac regeneration, diabetes, aging and metabolism.

Featured Publications

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