From the Labs

Sep 13, 2024 | From the Labs

A New Approach to Blood Cancers? Teaching the Immune System to Kill Mutant Stem Cells

Studying zebrafish, the Zon Lab is unpacking the signals that tell macrophages to eliminate mutated or diseased blood stem cells but encourage healthy ones to divide and proliferate. These signals might spawn new approaches to blood cancers like leukemia.

Sep 11, 2024 | From the Labs

Regenerative Therapy Project to Revolutionize Spinal Muscular Atrophy Treatment

A groundbreaking project involving the expertise of Harvard's Lee Rubin and David Mooney, and Boston Children’s Hospital’s Clifford Woolf, is set to redefine the treatment landscape for Spinal Muscular Atrophy (SMA) and potentially other neuromuscular diseases.

Sep 11, 2024 | From the Labs

Culturing Muscle Cells

Lee Rubin, Feodor Price and colleagues have pioneered a groundbreaking 3D organoid culture method for generating large numbers of adult skeletal muscle satellite cells in vitro.  

Aug 21, 2024 | From the Labs

Unveiling GlycoRNA: New Study Proves They Do Exist

Ryan Flynn's team has developed advanced techniques to provide conclusive evidence of glycoRNAs, motivating mechanistic work in the context of the immune system interactions and cell communication.

Jul 03, 2024 | From the Labs

Brain Chimeroids Reveal Susceptibility to Brain Triggers

With the ability to study the differential responses of human brain cells to various stimuli in a controlled and scalable manner, researchers have unlocked a potential revolution in understanding neuropsychiatric disorders.

May 22, 2024 | From the Labs

Mimicking Infection in Pregnant Mice Provokes Persistent Changes in Juvenile Brains

A new study provides insights into how activation of the maternal immune response during pregnancy might affect the development of unborn offspring, offering clues for further research into neurodevelopmental disorders.

Apr 01, 2024 | From the Labs

Fifteen Questions: Steve Hyman on the Genetics of Mental Health, Mind Reading, and Speaking his Mind

The Stem Cell and Regenerative Biology professor spoke with The Crimson about the ethics of neuroscience, mental health research, and his work as the former Director of the National Institute of Mental Health. “We have to do better in coming up with both preventive interventions and treatments for mental illness,” he says.

Mar 01, 2024 | From the Labs

Graduate Student Spotlight: Alan Baez Vazquez

Graduate student Alan Baez Vazquez is investigating how immune cells called macrophages contribute to repair of damaged lung tissue in Ruth Franklin’s lab.

Jan 11, 2024 | From the Labs

How to Make a Mammal

Studying the fates of cells, Sharad Ramanathan comes closer to understanding the biology of development.

Dec 14, 2023 | From the Labs

New Method Tags Cells with Location Coordinates for Single-Cell Studies

The technique, called Slide-tags, allows scientists to map the location of cells within tissues in standard single-cell experiments.