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Arlotta Lab

Investigating the biology of neuropsychiatric disorders

Researchers in the Arlotta laboratory are committed to making meaningful contributions to the study of neuropsychiatric disorders. We are based mainly in the Sherman-Fairchild building on Harvard’s Cambridge campus. We also carry out work a the Stanley Center of the Broad Institute.

Photo of Paola Arlotta
Principal Investigator (PI)

Dr. Arlotta is interested in understanding the molecular laws that govern the birth, differentiation and assembly of the cerebral cortex, the part of the brain that controls how we sense, move and think. She integrates developmental and evolutionary knowledge to investigate therapies for brain repair and for modeling neuropsychiatric disease.

Postdoctoral Fellows and Affiliates

Photo of Noelia Antón-Bolaños

Noelia Antón-Bolaños completed her graduate studies at the Universidad Miguel Hernández de Elche.

Photo of Michael Borrett

Michael Borrett obtained his PhD in neurodevelopment and stem cell biology at the University of Toronto. He currently studies human brain organoids in the context of autism spectrum disorder.

Photo of Nuria Dominguez Iturza

Nuria Dominguez-Iturza obtained her PhD in Neurosciences at the University of Leuven, investigating molecular mechanisms underlaying neurodevelopmental disorders.

Photo of Irene Faravelli

Irene Faravelli completed her Medical Degree and Neurology residency at the University of Milan.  She is interested in studying cortical organoids as a model for neurodevelopment and neurological diseases.

Photo of Rahel Kastli

Rahel Kastli completed her PhD at the University of Zurich, studying circuit formation of cortical interneurons. She is interested in using organoids to better understand neurodevelopmental disorders.

Photo of Amanda Kedaigle

Amanda Kedaigle is a Computational Biologist at the Broad Institute of MIT and Harvard who uses single cell sequencing technologies to study brain organoids. She completed her graduate studies at MIT.

Photo of Tyler Faits

Tyler is a Computational Scientist at the Broad Institute of MIT and Harvard, having earned his PhD from Boston University. He uses single cell sequencing technologies to study neurodevelopment in mouse and organoid models.

Photo of Michal Lipinski

Michal Lipinski completed his graduate studies at the Universidad Miguel Hernández de Elche.

Photo of Marta Montero Crespo

Marta Montero Crespo completed her PhD at the Cajal Institute, studying the synaptic organization of the human hippocampus and its alterations in Alzheimer’s disease. She is interested in understanding the ultrastructural features of human neurodevelopment.

Photo of Bridget Ostrem

Bridget Ostrem obtained her Ph.D. in Neuroscience and M.D. from the University of California, San Francisco. She then completed residency in Pediatric Neurology at Massachusetts General Hospital, and fellowship in Women’s Neurology at Brigham and Women’s Hospital. She uses mouse models and human brain organoids to interrogate how maternal factors such as infection and inflammation affect fetal brain development.

Photo of Bruna Paulsen

Bruna Paulsen was a postdoctoral fellow at Boston Children’s Hospital before joining the Arlotta Laboratory. She obtained her Ph.D from the Federal University of Rio de Janeiro, studying schizophrenia and neuronal differentiation.

Photo of Ashwin Shetty

Ashwin Shetty is a postdoctoral fellow at HSCRB and at the Broad Institute. He obtained his Ph.D. in developmental neuroscience from Tata Institute of Fundamental research in Mumbai.

Photo of Ana Uzquiano

Ana obtained her Ph.D. in developmental neurobiology from the Sorbonne University in Paris, studying cortical development and associated malformations.

Staff Scientists

Photo of Juliana Brown

Juliana Brown is a staff scientist and grant writer who brings her critical insights to every project in the lab.

Ph.D. Candidates

Photo of Zeke Benshirim

Zeke is interested in developing alternatives to animal research. He studied at Harvard College before entering the Ph.D. program in Biological and Biomedical Sciences.

Visiting Researchers

Photo of Niko Guirlinger

Niko Guirlinger completed his undergrad studies in bioengineering at EPFL, Switzerland. As a Bertarelli Fellow, he is currently pursuing a Master Thesis in Neurosciences at Harvard. He studies the developmental speed of corticogenesis using human and mouse cortical brain organoids.

Technical Staff

Photo of Sophia Andreadis

Sophia completed her undergraduate degree in Neuroscience & Behavior at Wesleyan University before joining the Arlotta Lab.

Photo of Lila Lyons

Lila completed her B.A in physics at UConn while working as a research assistant in neuroscience and cell biology at Yale School of medicine.

Photo of Sara Sime

Sara completed her undergraduate degree in Brain and Cognitive Sciences at MIT.

Photo of Vy Vuong

Vy studied Cell & Molecular Biology at Barnard College before joining the lab.

Faculty Assistant

Photo of Bill McCallum

Bill McCallum is Paola Arlotta’s trusty faculty assistant.

Lab Manager

Photo of Zachary Trayes-Gibson

Zachary Trayes-Gibson joined the Arlotta Lab from Massachusetts General Hospital, where he was a laboratory manager. Before MGH, he was a research assistant in Brigham and Women’s Hospital. He studied biological sciences at the University of Chicago.

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