News

Studying zebrafish, the Zon Lab is unpacking the signals that tell macrophages to eliminate mutated or diseased blood stem cells but encourage healthy ones to divide and proliferate. These signals might spawn new approaches to blood cancers like leukemia.

A groundbreaking project involving the expertise of Harvard's Lee Rubin and David Mooney, and Boston Children’s Hospital’s Clifford Woolf, is set to redefine the treatment landscape for Spinal Muscular Atrophy (SMA) and potentially other neuromuscular diseases.

Lee Rubin, Feodor Price and colleagues have pioneered a groundbreaking 3D organoid culture method for generating large numbers of adult skeletal muscle satellite cells in vitro.  

Ryan Flynn's team has developed advanced techniques to provide conclusive evidence of glycoRNAs, motivating mechanistic work in the context of the immune system interactions and cell communication.