Spotlight on YAP: Unlocking New Insights to Overcome the Barriers to Heart Regeneration. Circulation. 2025 Jan 07; 151(1):94-97.

Citation

Velayutham N, Lee RT. 2025. Spotlight on YAP: Unlocking New Insights to Overcome the Barriers to Heart Regeneration. Circulation. 151(1):94-97. Pubmed: 39723984 DOI:10.1161/CIRCULATIONAHA.124.072263

Abstract

This editorial refers to “Microtubules Sequester Acetylated YAP in the Cytoplasm and Inhibit Heart Regeneration” by Liu . and “YAP Overcomes Mechanical Barriers to Induce Mitotic Rounding and Adult Cardiomyocyte Division” by Morikawa

Related Faculty

Richard Lee, M.D.

Lee Lab

Rich Lee seeks to understand heart failure and metabolic diseases that accompany human aging, and translate that understanding into therapies. Lee is an active clinician, regularly treating patients at Brigham and Women’s Hospital.