Lo Celso C, Scadden DT. Stem cells remember their grade. Cell Stem Cell. 2007 Aug 16; 1(2):132-4.

Citation

Lo Celso C, Scadden DT. 2007. Stem cells remember their grade. Cell stem cell. 1(2):132-4. Pubmed: 18371344 DOI:10.1016/j.stem.2007.07.011

Abstract

The stem cell state is understood based on what cells do in performance assays, crude measures of a highly refined state. In this issue of Cell Stem Cell, Dykstra et al. (2007) reveal stem cell gradation and the extent to which that gradation is retained in stem cell daughters of hematopoietic stem cells.

Related Faculty

David Scadden, M.D.

Scadden Lab

David Scadden’s laboratory is dedicated to discovering the principles governing blood cell production, with the ultimate goal of guiding the development of therapies for blood disorders and cancer.