Designing an active learning exercise and implementing it in a classroom are arduous and can pose a challenge to instructors who hope to transform their lecture-based courses. Here, we describe a weekly writing assignment named Se/Feed (Self-Directed Learning with Feedback), in which students are asked to identify their own questions relevant to the lecture content and provide logical answers. Student surveys indicate that the assignment helped to engage students with the course material. Students reported that finding interesting questions was challenging yet rewarding and that the assignment facilitated personal interaction with the instructor. As the Se/Feed assignment does not require any preparation time or modification to existing course content, adopting the Se/Feed could help instructors incorporate active learning as part of their course.