HSCI iPS Core Facility

Disease-specific iPS cell lines make it possible to study the mechanisms of disease. The HSCI iPS core facility operates on a fee-for-service basis to provide investigators with customized iPS derivation and genome editing based on the latest stem cell technologies.

The HSCI iPS core facility offers three non-integrating technologies for reprogramming of a variety of somatic cell types:

• Sendai virus,
• miRNA, and
• modified mRNA episomal vector.

The facility also generates genome-engineered hESC or hiPS lines. They offer TALEN or CRISPR genome editing technologies to generate knock-out or knock-in lines for repair or introduction of mutations.

All HSCI iPS core facility services are available to the global research community.