Response to comment on "Genomic epidemiology of superspreading events in Austria reveals mutational dynamics and transmission properties of SARS-CoV-2". Sci Transl Med. 2021 10 27; 13(617):eabj3222.

Citation

Nicholson MD, Endler L, Popa A, Genger JW, Bock C, Michor F, Bergthaler A. 2021. Response to comment on "Genomic epidemiology of superspreading events in Austria reveals mutational dynamics and transmission properties of SARS-CoV-2". Science translational medicine. 13(617):eabj3222. Pubmed: 34705522 DOI:10.1126/scitranslmed.abj3222

Abstract

Further analysis of SARS-CoV-2 genome sequencing data identifies several highly recurrent genetic variants with low allele frequencies, which, if filtered out, provide estimates consistent with tighter transmission bottlenecks.

Related Faculty

Franziska Michor, Ph.D.

Michor Lab

Franziska Michor uses the tools of theoretical evolutionary biology, applied mathematics, statistics, and computational biology to address important questions in cancer research.