Melton DA. Applied Developmental Biology: Making Human Pancreatic Beta Cells for Diabetics. Curr Top Dev Biol. 2016; 117:65-73.

Citation

Melton DA. 2016. Applied Developmental Biology: Making Human Pancreatic Beta Cells for Diabetics. Current topics in developmental biology. 117:65-73. Pubmed: 26969972

Abstract

Understanding the genes and signaling pathways that determine the differentiation and fate of a cell is a central goal of developmental biology. Using that information to gain mastery over the fates of cells presents new approaches to cell transplantation and drug discovery for human diseases including diabetes.

Related Faculty

Douglas Melton, Ph.D.

Doug Melton is pursuing a cure for type 1 diabetes. His lab studies the developmental biology of the pancreas, using that information to grow and develop pancreatic cells (islets of Langerhans). In parallel, they investigate ways to protect beta cells from autoimmune attack.