Fast EM, Zon LI. Aging Hematopoietic Stem Cells Make Their History. Dev Cell. 2016 11 21; 39(4):390-391.

Citation

Fast EM, Zon LI. 2016. Aging Hematopoietic Stem Cells Make Their History. Developmental cell. 39(4):390-391. Pubmed: 27875682 DOI:S1534-5807(16)30789-4

Abstract

A major hallmark of aging is a decline in tissue regeneration. In a recent issue of Cell, Bernitz and colleagues (2016) determine the divisional history of hematopoietic stem cells (HSCs) to be a key player of regenerative potential in the aging mouse.

Related Faculty

Leonard Zon, M.D.

Zon Lab

The Zon laboratory aims to dissect how assaults to the hematopoietic system cause severe diseases such as leukemias, lymphomas, and anemias. They investigate hematopoietic development and disease using chemical screens, genetic screens, and analysis of novel transgenic lines in zebrafish.