Traver D, Zon LI. Walking the walk: migration and other common themes in blood and vascular development. Cell. 2002 Mar 22; 108(6):731-4.

Citation

Traver D, Zon LI. 2002. Walking the walk: migration and other common themes in blood and vascular development. Cell. 108(6):731-4. Pubmed: 11955426

Abstract

In this issue of Cell, a study by N. Cho and coworkers provides insight into the role of vascular endothelial growth factor (VEGF) signaling in Drosophila hematopoiesis. Their work suggests that an ancestral function of VEGF was to guide blood cell migration and highlights the conservation of at least one aspect of VEGF signaling during evolution.

Related Faculty

Leonard Zon, M.D.

Zon Lab

The Zon laboratory aims to dissect how assaults to the hematopoietic system cause severe diseases such as leukemias, lymphomas, and anemias. They investigate hematopoietic development and disease using chemical screens, genetic screens, and analysis of novel transgenic lines in zebrafish.